Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy

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منابع مشابه

Postoperative nonsteroidal anti-inflammatory drugs and risk of bleeding in pediatric intracapsular tonsillectomy.

OBJECTIVES In light of current FDA guidelines on opioid use in children, we sought to determine the risk of post-tonsillectomy hemorrhage (PTH) in children who received ibuprofen with acetaminophen versus those who received narcotic with acetaminophen for postoperative pain control. METHODS This was an IRB-approved retrospective chart review of patients at a tertiary-care pediatric center. Th...

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Nonsteroidal anti-inflammatory drugs.

Non-steroidal anti-inflammatory drugs (NSAIDs) are usually defined as those agents that inhibit one or more reactions involved in the production of prostaglandins and thromboxanes, important mediators of the inflammatory process in many organs and tissues. They find use in horses in the supportive treatment of a variety of systemic states and painful musculoskeletal or soft tissue conditions. T...

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Bleeding Zenker’s Diverticulum Ulcer from Nonsteroidal Anti-Inflammatory Drugs

A 70-year-old man presented for hematemesis that began the night prior. He reported several large bloody vomitus originating from his throat with a globus sensation. He was recently started on aspirin and clopidogrel for a transient ischemic attack. On arrival his vitals were stable and his physical exam was unremarkable. He was actively spitting up copious amounts of blood. Lab results showed ...

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Nonsteroidal Anti-Inflammatory Drugs and the Kidney

Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the isoenzymes COX-1 and COX-2 of cyclooxygenase (COX). Renal side effects (e.g., kidney function, fluid and urinary electrolyte excretion) vary with the extent of COX-2-COX-1 selectivity and the administered dose of these compounds. While young healthy subjects will rarely experience adverse renal effects with the use of NSAIDs, elderly pa...

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Nonsteroidal anti-inflammatory drugs in orthopaedics.

It is important for orthopaedic surgeons to understand the role of prostaglandins in bone physiology and the mechanism of action of nonsteroidal anti-inflammatory drugs and their role in fracture healing, fusion, osteointegration, and aseptic loosening. Nonsteroidal anti-inflammatory drugs have benefits and risks in orthopaedic use, and their effects should be considered.

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2013

ISSN: 1465-1858

DOI: 10.1002/14651858.cd003591.pub3